Modacharge 200 mg

What is Modacharge 200 mg?

Modacharge 200 mg is an alertness enhancing medication indicated for the treatment of excessive daytime sleepiness associated with Narcolepsy, Shift Worker Sleep Disorder and Obstructive Sleep Apnea. Although its exact mechanism is not known, Modafinil works by affecting several neurotransmitters in the brain that regulate the sleep-wake cycle.

How does it work?

Modafinil acts as a weak but selective dopamine inhibitor, binding to the dopamine transporter and blocks dopamine clearance that boosts focus and wakefulness. Modafinil stimulates orexin which plays an important role in regulating the sleep-wake cycle. GABA (Gamma-aminobutyric acid) is a major inhibitory neurotransmitter that regulates sleep. Modafinil reduces the levels of GABA and thus it prevents the brain from slipping into sleep. 

Key Features

COMPOSITION

Active ingredient: Modafinil 200 mg
Inactive ingredients: Microcrystalline cellulose, Croscarmellose sodium, Povidone, Magnesium stearate, Lactose Monohydrate, Pregelatinized starch

What is it used for?
Modacharge 200 mg are indicated to improve wakefulness in adult patients with excessive sleepiness that is due to Narcolepsy, Obstructive Sleep Apnea and Shift Worker Sleep Disorder. 

DOSAGE 

Dosage in Narcolepsy and Obstructive Sleep Apnea
The recommended dosage for Narcolepsy and Obstructive Sleep Apnea is 200 mg taken orally once in the morning daily. 

Dosage in Shift Worker Sleep Disorder (SWSD)
The recommended dosage for SWSD is 200 mg taken orally once a day approximately one hour prior to the shift begins. 

SIDE EFFECTS 

• Headache
• Nausea
• Diarrhea
• Back pain 
• Anorexia
• Chest pain 
• Hypertension
• Palpitations
• Tachycardia (increased heart beat)
• Chills
• Confusion
• Depression

INTERACTIONS 

Key Drug Interactions 

• Modafinil can reduce the effectiveness of birth control pills, devices, implants or patches, necessitating the need for alternative methods of birth control. 
• Blood thinners like warfarin when used together can increase the risk of bleeding. 
• Anticonvulsants like phenytoin, phenobarbital and carbamazepine can make modafinil less effective while unpredictably altering seizure control. 
• Antidepressants & Anxiety medications like diazepam or clomipramine can increase side effects. 

Lifestyle & Dietary Interactions 

• Combining alcohol with modafinil can increase adverse effects and reduce the therapeutic benefits of the medication
• Grapefruit or grapefruit juice can increase the levels of modafinil in the body as it blocks the breakdown of modafinil. 
• Excessive caffeine intake (coffee, energy drinks, tea) while on modafinil can lead to palpitations, rapid heart rate, nervousness, and severe nausea 

PRECAUTIONS & WARNINGS 

• Individuals who have a known allergy to modafinil should not ingest Modacharge 200 mg.
• Use with caution if you have a history of depression, mania or psychosis. 
• It’s best to not operate any kind of heavy machinery after taking Modacharge 200 mg, as it can hamper your judgement or response time. 
• Individuals who have had a history of liver conditions should inform doctors  since modafinil is primarily metabolised in the liver. They may require a lower dosage. 
• The medication should not be used by pregnant or breastfeeding women. 
• Avoid self-administration. 

CONCLUSION 

Modacharge 200 mg provides a powerful tool for adults who experience excessive daytime sleepiness to stay alert and awake. The active ingredient present in it is Modafinil which acts on neurotransmitters to promote wakefulness and mental clarity during the day. Modacharge 200 mg can be an effective component of treatment for sleep disorders and enhancing daily performance if taken as prescribed. 

FAQs

1.  What is Modacharge 200 mg used for?
Modacharge 200 mg is indicated to enhance wakefulness in adult patients who have excessive daytime sleepiness. 

2. What is the onset of action of Modacharge 200 mg?
The onset of action of Modacharge 200 mg is 30 to 60 minutes. 

3. Can Modacharge 200 mg be taken on an empty stomach?
Yes. Modacharge 200 mg can be taken with or without food.

4. Is Modacharge 200 mg good for night shift workers?
Yes. Modacharge 200 mg can be used in adults with Shift Work Sleep Disorder (SWSD) and is usually taken about an hour prior to the work shift. 

5. Can Modafinil cause hypersexuality?
Yes. Although rare, Modafinil may cause hypersexuality.